| Date | Location | Result | |
| 02/28/22 | Pembroke, N.C. / Lumbee Bank Court | Emmanuel 69, UNC Pembroke 67 | Box score |
| 02/24/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 68, North Greenville 41 | Box score |
| 02/22/22 | Wilson, N.C. / Wilson Gymnasium | Barton 79, UNC Pembroke 60 | Box score |
| 02/19/22 | Due West, S.C. / Belk Arena | UNC Pembroke 55, Erskine 42 | Box score |
| 02/18/22 | Central, S.C. / Tysinger Gymnasium | UNC Pembroke 69, Southern Wesleyan 51 | Box score |
| 02/16/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 63, Mount Olive 62 | Box score |
| 02/12/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 61, Belmont Abbey 57 | Box score |
| 02/11/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 67, Southern Wesleyan 64 | Box score |
| 02/05/22 | Banner Elk, N.C. / Williams Gymnasium | Lees-McRae 79, UNC Pembroke 70 | Box score |
| 02/04/22 | Bristol, Tenn. / Student Center Complex | UNC Pembroke 84, King 64 | Box score |
| 01/29/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 70, Emmanuel 64 | Box score |
| 01/26/22 | Florence, S.C. / Smith University Center | Francis Marion 79, UNC Pembroke 74 | Box score |
| 01/22/22 | Tigerville, S.C. / Hayes Gymnasium | UNC Pembroke 64, North Greenville 39 | Box score |
| 01/21/22 | Spartanburg, S.C. / Hannah Gym | UNC Pembroke 57, Converse 42 | Box score |
| 01/17/22 | Mount Olive, N.C. / Kornegay Arena | Mount Olive 61, UNC Pembroke 53 | Box score |
| 01/13/22 | Pembroke, N.C. / Lumbee Bank Court | Barton 59, UNC Pembroke 50 | Box score |
| 01/06/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 66, Francis Marion 49 | Box score |
| 01/04/22 | Pembroke, N.C. / Lumbee Bank Court | Chowan 62, UNC Pembroke 54 | Box score |
| 12/18/21 | Belmont, N.C. / Wheeler Center | UNC Pembroke 68, Belmont Abbey 52 | Box score |
| 12/15/21 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 76, Converse 40 | Box score |
| 12/12/21 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 63, Saint Augustine's 40 | Box score |
| 12/04/21 | Pembroke, N.C. / Lumbee Bank Court | King 80, UNC Pembroke 76 | Box score |
| 12/03/21 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 66, Lees-McRae 32 | Box score |
| 11/30/21 | Murfreesboro, N.C. / Bob Burke Court | UNC Pembroke 65, Chowan 54 | Box score |
| 11/23/21 | Royston, Ga. / Shaw Athletic Center | UNC Pembroke 70, Emmanuel 53 | Box score |
| 11/20/21 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 59, Erskine 49 | Box score |
| 11/17/21 | Fayetteville, N.C. / Capel Arena | Fayetteville State 55, UNC Pembroke 47 | Box score |
| 11/13/21 | Pembroke, N.C. / Eleazer Arena | Wingate 66, UNC Pembroke 59 | Box score |
| 11/12/21 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 66, Coker 51 | Box score |